Shedding New Light on the Platelet Storage Lesion
نویسندگان
چکیده
منابع مشابه
Shedding New Light on the Platelet Storage Lesion.
The lifespan of circulating endogenous platelets is determined by a combination of random platelet removal and a nonrandom aging mechanism after which senescent platelets are removed by the reticuloendothelial system. At least a portion of platelet senescence is regulated by an intrinsic apoptotic pathway that acts as an internal timer. Platelets contain members of the antiapoptotic Bcl-2 famil...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2016
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.116.308095